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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab9604a9b956dcd4c16fc130d3456aa376dc0d6e4de355064b2cf85ccb84a679' 
  AND token = 'FrV2nOft320jyM5zLwRF1ipPP5RVZEPf4WE50ueCDyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}