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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3861b4a677b93fb94093385962f6f15b6421df4225c99d2c1fad020e1d5dfbc1' 
  AND token = 'YB33tCHIR93m37NNVDgcjhmYux45klQoUA7k4qmJtDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}