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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1e08d75b2f26a08339974403bbddda380ae856228c20039005c7f7974e9161' 
  AND token = 'JKgf2he/rJkKw402jtBeVjwFt8kHbB3Cp4hXReiB6IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}