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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d89a20fee0dd1cc97b827e9fdc5729fcb997311d0909755af4f10624df5110c' 
  AND token = 'eR5z2Epzem0NJP3+RxuUJzgcgCbjZFtumdIUPSVTbKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}