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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad778916e9ee5b41c5ac8f92ebcaea915e70230a1909d0472348544851ed5afd' 
  AND token = '6OwzXT4URVaU/s7KBh1Z/pSCPcUZhWBCVQHr1Cd5JCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}