SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa6ae0618bc693bf373faa8b451317a07780159fc581d282bdeeafcd4f1eb5c' 
  AND token = 'k0IOIzrZl7YG+MyCaqHBSdtInU0mB/Q8MqtD67V5Vps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}