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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e04bd53458b76cb699bf1f948d4518053078dd902939178656451c34dfe529' 
  AND token = '6sscvmeDwcZvCDN2VLSMR41SYTh/N4N/BtgbfGaAnoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}