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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3fcb2fe4fdca434e0d54ef4d3c7bdc717b77b2b3a6c108787f8f661210d768' 
  AND token = '2chUopLVIU6VEzhbwEyy2K7nFm+11AQkh0EiScsERK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}