SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc43412a09cae27078eb05fa87a3a462c5af5846e78f3d9381bd42a3d36a980' 
  AND token = 'dIFoBSP4HANaFQeSDoH5Xs9bY7iVnRN26e2YkRb9ucY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}