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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f46d7f4ef22973d220943e4a2d67e0380fb55c9e7d32c85b5bcd97117cdb7921' 
  AND token = 'IIE4N1EQ6OTyZOol4MvgyKNHTpNrKJcFaBXo/YBBwKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}