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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46145bd36a5c62adc0b44f151c369578c1f3b39a9934ebbdec0b0e1e8cd17d8c' 
  AND token = 'nn3/nWW//5aeTfv2mtky/fYEBSfK3hDhqfxnoiilA5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}