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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f515ad47e5a5f8f696b906693b7e7f0d05966981e899bd2b672044b6055dceeb' 
  AND token = 'UTC5e/lXMTfnO6DnLFnRNHn71gJG3NHvd2Cq56nncvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}