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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d2f8067151717b28c7135b90a1428849b2a3c4d4733136e50446e410c76495' 
  AND token = 'RhtLZolrS6Q8OUzVXqtKph7pr7egPB12hmtEntbrvj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}