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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acaefe9cf4f786bbebd8a9f0ac042bbc81823f4b44b422fd7bf026d5726d3f5b' 
  AND token = '9qcyRfb+5eOsLo3v5I758AFEpo6BR2pKX1XN9ULplnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}