SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581ee0578f21443c9b5201aee5256b6d4b3e0e054b0609d46bdb4be0d8925f8e' 
  AND token = 'lK1InjivzyR7ztNoa3ZRsUGsACmryttPnPiVjLEOheA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}