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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dfe749d87ac1594ac8f021a43b0014c5239ab75ae84b426aea2fa8116268064' 
  AND token = 'oYTJVqrW+GUcdp/bmqLr3nn/m1+MWBdpOnhxPym30+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}