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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5749fe6a346ec454ef7f6f85bd67dbd3c43990dbf729a34f50650a7781ab5637' 
  AND token = 'TNAi2bCqB4xMT+JmhvO+83kMDkuD7p+kWRdNbWrHeR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}