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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542995973f342032056727d36a1cfc3de26f23bc2280957a1fa7b951bb1d01cc' 
  AND token = 'gIL5kUYvjis5tUAaSd7WBEd+xeJwRyMeA6D2+yqoNL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}