SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f88a40dfd5031546025a081ed3bd3de29891ccf2d47e0d0d9b8de238ddaffc' 
  AND token = 'ql7vFcZTRFVX8cDsVpRE2S0IJ+IMErceFW3JhoQzOHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}