SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9963e927ae0ad2e9f1d322c6d710c39f73cb8af1f589ec8e38aae712b33a106b' 
  AND token = 'U+v2m+dITOP0AG3ytsGaYhLM7GNv1mY6NcttbNLOl6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}