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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09cc5161f87b508217a5fb211f1278be2bd5aea356af04c641b05acf1110b0f3' 
  AND token = 'MIhs2A6a+tNv89vGK7tqSepZRif+8VahOMN3QCHSR7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}