SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4f9e8a57e145a5c2d439008994deb866bfd6954bed262035748efa588ec659' 
  AND token = 'DlZpAA8Ad6/2ZYNmCDL6fMMlh4/wT64MXL3+RLkJCTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}