SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e305390d41dec5c9b9abfda418d2057a286ccfd64b655d68403341019fb5e00' 
  AND token = 'wFdHG+THHVHdXUXrDxYX7vQ8uB0fw9Rb/z0PSFD+MBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}