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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e41d502a43d943e9bef1c128b534545de8dbfb8f2493bc5d9314f0feda3992b' 
  AND token = 'Chzq3xjQIkzc9Sw8IB2jH2CCEdgcnaDOETJHO2HxUBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}