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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217ce3a80ffc014dc03ec1b3e8514cd5127f5dfe2714d28e47600ae67033ada3' 
  AND token = 'W5CNmdN039M6X9U2MtgB/U5VJVH8lhpaG73zsK+6wpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}