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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c7464bd973c51dde33b3b9c24aaf4aaeb05aebec1cba856209c5484bba7b43' 
  AND token = 'sLjRYhN7/0ABC0n+4aW2wYXzA66Su0OEZp+u0wwVQhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}