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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d25d3cdc013310adb70453b7a32d24b09541165b3b341a8a18dc3dc54b078d' 
  AND token = 'pBf+qCWA/WBurmK/zGgdXmhW+0scVa2NKLiW77W/67M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}