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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8484aface696608ead1a485cfefeafa6b80cc1f0152c8826775872f091cc8053' 
  AND token = '0bG/V0q7VPcbMTX+899G3copfgyqBB15MSFEnsnDUzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}