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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3aa277d4abd6b7f063c106072a19d37290e3ccf5bea683bd9acc1cb38a9ac52' 
  AND token = 'VFH5c/W5rNOKFf7G6HtP5phVMdNciWi1A9Aa+D9KzD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}