SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b49aed3d027d1c359652fc4123e2ce64a5d0a87f40ef20622e70b87b773872b' 
  AND token = 'xN1NB9PxKc7m4Bj4BDWq+gwkRpQmcc9x3jEWZ1LhffU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}