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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd332448c42003ffcda72086bc4cb23da2c4a2b56cc5cd7043933764918dd18b' 
  AND token = 'UOTEDagRSWcc8GEQ2wtqLUQh+yR88LPOPT0y0P+Ko44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}