SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75955b4719d5329c1558b419a378595ecd98aea6590eb1ada2b9d9931ab5b5d4' 
  AND token = 'anaL6m2K7NQwefjkpDG7qnez/0yb+iZf6ZI/eyzYCO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}