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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3309482aa865bf057fb9e9a8586b532dcc231916b8bd839880c6cd4a2b5745' 
  AND token = 'we8kxnm3bHkFZO387FIm/i0AjDxW7StoZ0Tw8gP533A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}