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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1823b0eac42147a9004234c00bc52d62b8cb1a010f29440fc0c0a4f91471d6b' 
  AND token = 'dqt1wY5Xns9Q0Sjb5RTuc90VZBaZ2EYJ9azAQjrcMVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}