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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba100cf2c2e8295aa002404234c847c3893af18f86a9fa0fe2324a86304b862' 
  AND token = 'YtCD+CXt2c0yvy7nHpicOKumRfcZWkC55+IAsM/IqhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}