SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d217ddfa6fccaad275617e1205665631f84732e72173ae52a3ed0ba228bce50' 
  AND token = '0JL0N8cUgzvg/yN6XRl80EQlFFxzh6nPFaSBeKc9gXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}