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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28461f485f82c06361cf404ab9d465a70449c01048c8735705def94084db5297' 
  AND token = 'kk+9kAZ8k5I6tR1IiMBzUvWexvDswFXA/K0AZ3y0q+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}