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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b22f545f3ada71db487014a551ce53d0f3cb3385e9325889017708b1ceaafd' 
  AND token = 'Ak5H7f5n4S6OSiR74jj611y59Z7/rERU9/r6NwK6u6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}