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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332fc998c3f486ce7535140254316a7ef890e5e06b8a9b4f7036ec341528de90' 
  AND token = 'VNcmZKg6I0ABAyQaLMiV/qicDHmiMyCfVExDIeXScMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}