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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8091e9f9832d40609079e39a47724abddf7609410870094e91a4bddf8ab2b21' 
  AND token = 'oTOMP0UmyeWoXMupgnaifnTfxoTUINCP4qrU0ZXL5Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}