SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a45381df9e8bb36e5ae5f32e32c625a99934d4c098613e3731744c00244b8ab' 
  AND token = 'SUU6qmWz11lgqA826sPONFEc5Wjw0NoPZ5iFbSj219E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}