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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b326d07a4ab38b24a5b9b71d19ecfa7e9977e711681580c46e80d25575567f' 
  AND token = 'cVkjLPYXiiy+4L63n7mmGQSOZXIm9xrGt6EDQdR2McE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}