SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa9d69cb5d723b1ca6789821bbd825a4b5ea0552796015a05d494f62fda685e4' 
  AND token = 'zp0O3b3bu5MwIg/Bcc32PuX5UmALBwFCxAi9KqRzKOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}