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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1204b9556c0bd97b214e2a378339d908e1439c311bcad62f2e5aa5b348b369f6' 
  AND token = 'yipLQrfyjM3IHW16EYH5yhwfYtyjrSksqx0EUW8+X2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}