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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1ed98f90e121dd0af528a299925f00cf9136ffaacfe368ac9c9562a3ac73b8' 
  AND token = 'OqEHuhokf2rNb364//EzEA+0Qfz3B+ifw4V4RzGN1/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}