SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b47afac50b063bc977408261a94315f6683776f41f486d9fb1641c1c7a9546' 
  AND token = 'm3OnPlF4thSKzwYRhFnR7gM9ePlRXMEfF/y7SNsuCEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}