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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8e00c285c739b66c1b9a35dc17e84d288c684cd19a9a1b88f4ba1cbee40a72' 
  AND token = 'NFZ4R1M3K3DD2h9Bq+Wuw+QbEB99Q6DfrtXs2uCDIZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}