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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980ab4c60ab3e1c39736f37ea598c2b6a31fa7d8a2794d249e76e7c8101d389a' 
  AND token = '7MYqYN/YYIdx4a9Jd8O8lU40HZF0YuGyxYuQdglOnKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}