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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50873680864f5bf76c8a0a005688e231c35f7492ebcac31a1845b21d0701da7b' 
  AND token = '3b6mz4GGpS3lU/j46Sp7CEQvTFV8WXuYEv2bJCrbQxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}