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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2734cd88fb4d02a83cd45059b3a05b91537b18a3f22863a54b670b29b11d5ba3' 
  AND token = '1GjLz6s+G48bT7Sx44MAl1qhifwBpoW1nKqx775kHiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}